BE
Jupiler League
| Sat | 01-10-2022 | 16:00 | OH Leuven | Royale Union St |
| Sat | 01-10-2022 | 18:15 | KV Oostende | KRC Genk |
| Sat | 01-10-2022 | 18:15 | KVC Westerlo | SV Zulte Warege |
| Sat | 01-10-2022 | 20:45 | Club Brugge | KV Mechelen |
| Sun | 02-10-2022 | 13:30 | RSC Anderlecht | RSC Charleroi |
| Sun | 02-10-2022 | 16:00 | KAA Gent | Cercle Brugge |
| Sun | 02-10-2022 | 18:30 | KV Kortrijk | Antwerp |
| Sun | 02-10-2022 | 21:00 | Sint-Truidense | KAS Eupen |
| Fri | 07-10-2022 | 20:45 | Antwerp | Sint-Truidense |
EN
Premier League
| Sat | 01-10-2022 | 13:30 | Arsenal | Tottenham Hotsp |
| Sat | 01-10-2022 | 16:00 | Bournemouth | Brentford |
| Sat | 01-10-2022 | 16:00 | Crystal Palace | Chelsea |
| Sat | 01-10-2022 | 16:00 | Fulham | Newcastle Unite |
| Sat | 01-10-2022 | 16:00 | Liverpool | Brighton and Ho |
| Sat | 01-10-2022 | 16:00 | Southampton | Everton |
| Sat | 01-10-2022 | 18:30 | West Ham United | Wolves |
| Sun | 02-10-2022 | 15:00 | Manchester City | Manchester Unit |
| Sun | 02-10-2022 | 17:30 | Leeds | Aston Villa |
FR
Ligue 1
| Sat | 01-10-2022 | 17:00 | Strasbourg | Stade Rennais F |
| Sat | 01-10-2022 | 21:00 | Paris Saint Ger | OGC Nice |
| Sun | 02-10-2022 | 13:00 | FC Lorient | Lille OSC |
| Sun | 02-10-2022 | 15:00 | AC Ajaccio | Clermont Foot |
| Sun | 02-10-2022 | 15:00 | AJ Auxerre | Stade Brest 29 |
| Sun | 02-10-2022 | 15:00 | ESTAC Troyes | Stade Reims |
| Sun | 02-10-2022 | 15:00 | Toulouse | Montpellier HSC |
| Sun | 02-10-2022 | 17:05 | AS Monaco | FC Nantes |
| Sun | 02-10-2022 | 20:45 | RC Lens | Lyon |
GE
Bundesliga
| Sat | 01-10-2022 | 15:30 | RB Leipzig | VfL Bochum |
| Sat | 01-10-2022 | 15:30 | SC Freiburg | 1.FSV Mainz 05 |
| Sat | 01-10-2022 | 15:30 | 1.FC Köln | Borussia Dortmu |
| Sat | 01-10-2022 | 15:30 | Eintracht Frank | 1.FC Union Berl |
| Sat | 01-10-2022 | 15:30 | VfL Wolfsburg | VfB Stuttgart |
| Sat | 01-10-2022 | 18:30 | Werder Bremen | Borussia Mönche |
| Sun | 02-10-2022 | 15:30 | Hertha BSC | TSG 1899 Hoffen |
| Sun | 02-10-2022 | 17:30 | FC Schalke 04 | FC Augsburg |
| Fri | 07-10-2022 | 20:30 | TSG 1899 Hoffen | Werder Bremen |
IT
Serie A
| Sun | 02-10-2022 | 15:00 | Atalanta Bergam | Fiorentina ACF |
| Sun | 02-10-2022 | 15:00 | Empoli FC | AC Milan |
| Sun | 02-10-2022 | 15:00 | Hellas Verona F | Udinese Calcio |
| Sun | 02-10-2022 | 15:00 | Inter Milan | AS Roma |
| Sun | 02-10-2022 | 15:00 | Juventus | Bologna FC |
| Sun | 02-10-2022 | 15:00 | Lazio Roma | Spezia |
| Sun | 02-10-2022 | 15:00 | Sampdoria | Monza |
| Sun | 02-10-2022 | 15:00 | Sassuolo | Salernitana |
| Sun | 02-10-2022 | 15:00 | Napoli | FC Torino |
NL
Eredivisie
| Sat | 01-10-2022 | 16:30 | SC Cambuur | PSV |
| Sat | 01-10-2022 | 18:45 | FC Groningen | AZ |
| Sat | 01-10-2022 | 20:00 | Ajax | Go Ahead Eagles |
| Sat | 01-10-2022 | 21:00 | FC Twente | Vitesse |
| Sun | 02-10-2022 | 12:15 | Fortuna Sittard | FC Volendam |
| Sun | 02-10-2022 | 14:30 | Excelsior | FC Utrecht |
| Sun | 02-10-2022 | 14:30 | NEC | Feyenoord |
| Sun | 02-10-2022 | 16:45 | RKC Waalwijk | Sparta Rotterda |
| Sun | 02-10-2022 | 20:00 | FC Emmen | SC Heerenveen |
SP
Primera Division
| Sun | 02-10-2022 | 21:00 | Athletic Bilbao | Almeria UD |
| Sun | 02-10-2022 | 21:00 | Celta de Vigo | Real Betis |
| Sun | 02-10-2022 | 21:00 | Espanyol de Bar | Valencia |
| Sun | 02-10-2022 | 21:00 | Cádiz CF | Villarreal CF |
| Sun | 02-10-2022 | 21:00 | Getafe CF | Real Valladolid |
| Sun | 02-10-2022 | 21:00 | Girona FC | Real Sociedad |
| Sun | 02-10-2022 | 21:00 | Sevilla FC | Atletico Madrid |
| Sun | 02-10-2022 | 21:00 | Rayo Vallecano | Elche CF |
| Sun | 02-10-2022 | 21:00 | Real Club Depor | FC Barcelona |
