BE
Jupiler League
| Fri | 22-10-2021 | 20:45 | RFC Seraing | RSC Charleroi |
| Sat | 23-10-2021 | 16:15 | Cercle Brugge | Standard Ličge |
| Sat | 23-10-2021 | 18:30 | KV Kortrijk | KV Oostende |
| Sat | 23-10-2021 | 18:30 | KV Mechelen | SV Zulte Warege |
| Sat | 23-10-2021 | 20:45 | KAS Eupen | Royale Union St |
| Sun | 24-10-2021 | 13:30 | Antwerp | Club Brugge |
| Sun | 24-10-2021 | 16:00 | RSC Anderlecht | Beerschot-Wilri |
| Sun | 24-10-2021 | 18:30 | KRC Genk | KAA Gent |
| Sun | 24-10-2021 | 21:00 | OH Leuven | Sint-Truidense |
EN
Premier League
| Fri | 22-10-2021 | 21:00 | Arsenal | Aston Villa |
| Sat | 23-10-2021 | 13:30 | Chelsea | Norwich City |
| Sat | 23-10-2021 | 16:00 | Crystal Palace | Newcastle Unite |
| Sat | 23-10-2021 | 16:00 | Everton | Watford |
| Sat | 23-10-2021 | 16:00 | Leeds | Wolves |
| Sat | 23-10-2021 | 16:00 | Southampton | Burnley |
| Sat | 23-10-2021 | 18:30 | Brighton and Ho | Manchester City |
| Sun | 24-10-2021 | 15:00 | Brentford | Leicester City |
| Sun | 24-10-2021 | 15:00 | West Ham United | Tottenham Hotsp |
FR
Ligue 1
| Fri | 22-10-2021 | 21:00 | AS Saint-Étienn | Angers SCO |
| Sat | 23-10-2021 | 17:00 | FC Nantes | Clermont Foot |
| Sat | 23-10-2021 | 21:00 | Lille OSC | Stade Brest 29 |
| Sun | 24-10-2021 | 13:00 | OGC Nice | Lyon |
| Sun | 24-10-2021 | 15:00 | RC Lens | FC Metz |
| Sun | 24-10-2021 | 15:00 | FC Lorient | Girondins Borde |
| Sun | 24-10-2021 | 15:00 | Stade Reims | ESTAC Troyes |
| Sun | 24-10-2021 | 15:00 | Stade Rennais F | Strasbourg |
| Sun | 24-10-2021 | 17:00 | AS Monaco | Montpellier HSC |
GE
Bundesliga
| Fri | 22-10-2021 | 20:30 | 1.FSV Mainz 05 | FC Augsburg |
| Sat | 23-10-2021 | 15:30 | Bayern München | TSG 1899 Hoffen |
| Sat | 23-10-2021 | 15:30 | RB Leipzig | SpVgg Greuther |
| Sat | 23-10-2021 | 15:30 | VfL Wolfsburg | SC Freiburg |
| Sat | 23-10-2021 | 15:30 | Arminia Bielefe | Borussia Dortmu |
| Sat | 23-10-2021 | 18:30 | Hertha BSC | Borussia Mönche |
| Sun | 24-10-2021 | 15:30 | 1.FC Köln | Bayer Leverkuse |
| Sun | 24-10-2021 | 17:30 | VfB Stuttgart | 1.FC Union Berl |
| Sun | 24-10-2021 | 19:30 | VfL Bochum | Eintracht Frank |
IT
Serie A
| Fri | 22-10-2021 | 18:30 | FC Torino | Genoa CFC |
| Fri | 22-10-2021 | 20:45 | Sampdoria | Spezia |
| Sat | 23-10-2021 | 15:00 | Salernitana | Empoli FC |
| Sat | 23-10-2021 | 18:00 | Sassuolo | Venezia |
| Sat | 23-10-2021 | 20:45 | Bologna FC | AC Milan |
| Sun | 24-10-2021 | 12:30 | Atalanta Bergam | Udinese Calcio |
| Sun | 24-10-2021 | 15:00 | Fiorentina ACF | Cagliari Calcio |
| Sun | 24-10-2021 | 15:00 | Hellas Verona F | Lazio Roma |
| Sun | 24-10-2021 | 18:00 | AS Roma | Napoli |
NL
Eredivisie
| Fri | 22-10-2021 | 20:00 | Willem II | Fortuna Sittard |
| Sat | 23-10-2021 | 18:45 | FC Utrecht | SC Heerenveen |
| Sat | 23-10-2021 | 20:00 | PEC Zwolle | Heracles Almelo |
| Sat | 23-10-2021 | 21:00 | RKC Waalwijk | Sparta Rotterda |
| Sun | 24-10-2021 | 12:15 | FC Twente | NEC |
| Sun | 24-10-2021 | 14:30 | SC Cambuur | Feyenoord |
| Sun | 24-10-2021 | 14:30 | Vitesse | Go Ahead Eagles |
| Sun | 24-10-2021 | 16:45 | Ajax | PSV |
| Sun | 24-10-2021 | 20:00 | FC Groningen | AZ |
PO
Superliga
| Fri | 22-10-2021 | 21:15 | Vitória de Guim | Maritimo |
| Sat | 23-10-2021 | 16:30 | Santa Clara | FC Famalicăo |
| Sat | 23-10-2021 | 19:00 | CD Tondela | FC Porto |
| Sat | 23-10-2021 | 21:30 | Sporting Lisbon | Moreirense FC |
| Sun | 24-10-2021 | 16:30 | Paços de Ferrei | FC Arouca |
| Sun | 24-10-2021 | 19:00 | FC Vizela | Benfica S.L. |
| Sun | 24-10-2021 | 21:30 | Portimonense SC | Estoril Praia G |
| Mon | 25-10-2021 | 20:00 | Gil Vicente FC | Sporting Braga |
| Mon | 25-10-2021 | 22:15 | Boavista FC | Belenenses CF |
RU
Premier Liga 1
| Fri | 22-10-2021 | 19:00 | Zenit St Peters | FC Spartak Mosk |
| Fri | 22-10-2021 | 19:00 | FC Rostov | FK Arsenal Tula |
| Fri | 22-10-2021 | 19:00 | CSKA Moscow | Krylya Sovetov |
| Fri | 22-10-2021 | 19:00 | Dynamo Moscow F | Khimki |
| Fri | 22-10-2021 | 19:00 | Lokomotiv Moskv | PFC Sochi |
| Fri | 22-10-2021 | 19:00 | Akhmat Grozny | Ural |
| Fri | 22-10-2021 | 19:00 | Nizhny Novgorod | Krasnodar |
| Fri | 22-10-2021 | 19:00 | Ufa | Rubin Kazan |
| Fri | 29-10-2021 | 19:00 | Zenit St Peters | Dynamo Moscow F |
SC
Premier League
| Sat | 23-10-2021 | 16:00 | Aberdeen | Hibernian FC |
| Sat | 23-10-2021 | 16:00 | Celtic FC | St. Johnstone |
| Sat | 23-10-2021 | 16:00 | Dundee United | Motherwell FC |
| Sat | 23-10-2021 | 16:00 | Heart of Midlot | Dundee FC |
| Sat | 23-10-2021 | 16:00 | Ross County FC | Livingston |
| Sat | 23-10-2021 | 16:00 | St Mirren | Rangers FC |
| Wed | 27-10-2021 | 20:45 | Dundee FC | Ross County FC |
| Wed | 27-10-2021 | 20:45 | Hibernian FC | Celtic FC |
| Wed | 27-10-2021 | 20:45 | Livingston | Dundee United |
SP
Primera Division
| Fri | 22-10-2021 | 21:00 | CA Osasuna | Granada CF |
| Sat | 23-10-2021 | 14:00 | Valencia | Real Club Depor |
| Sat | 23-10-2021 | 16:15 | Cádiz CF | Deportivo Alavé |
| Sat | 23-10-2021 | 18:30 | Elche CF | Espanyol de Bar |
| Sat | 23-10-2021 | 21:00 | Athletic Bilbao | Villarreal CF |
| Sun | 24-10-2021 | 14:00 | Sevilla FC | Levante UD |
| Sun | 24-10-2021 | 16:15 | FC Barcelona | Real Madrid |
| Sun | 24-10-2021 | 18:30 | Real Betis | Rayo Vallecano |
| Sun | 24-10-2021 | 21:00 | Atletico Madrid | Real Sociedad |
US
Major League
| Thu | 21-10-2021 | 01:30 | Orlando City SC | CF Montreal |
| Thu | 21-10-2021 | 01:30 | Atlanta United | New York City F |
| Thu | 21-10-2021 | 01:30 | FC Cincinnati | Chicago Fire |
| Thu | 21-10-2021 | 02:00 | DC United | New England Rev |
| Thu | 21-10-2021 | 02:00 | Minnesota Unite | Philadelphia Un |
| Thu | 21-10-2021 | 02:00 | FC Dallas | Los Angeles FC |
| Thu | 21-10-2021 | 02:30 | Nashville SC | Columbus Crew |
| Thu | 21-10-2021 | 02:30 | Houston Dynamo | LA Galaxy |
| Thu | 21-10-2021 | 03:00 | Colorado Rapids | Seattle Sounder |
#Eredivisie
| P | Team | PL | W | D | L | Pts | F | A | Last 5 matches |
| 1 | Ajax | 9 | 7 | 1 | 1 | 22 | 32 | 2 | |
| 2 | PSV | 9 | 7 | 0 | 2 | 21 | 22 | 12 | |
| 3 | FC Utrecht | 9 | 5 | 2 | 2 | 17 | 19 | 10 | |
| 4 | Willem II | 9 | 5 | 2 | 2 | 17 | 13 | 11 | |
| 5 | Feyenoord | 8 | 5 | 1 | 2 | 16 | 22 | 11 | |
| 6 | Vitesse | 9 | 5 | 1 | 3 | 16 | 9 | 15 | |
| 7 | FC Twente | 9 | 4 | 3 | 2 | 15 | 15 | 11 | |
| 8 | SC Heerenveen | 9 | 4 | 1 | 4 | 13 | 11 | 14 | |
| 9 | AZ | 8 | 4 | 0 | 4 | 12 | 19 | 13 | |
| 10 | SC Cambuur | 9 | 4 | 0 | 5 | 12 | 16 | 22 | |
| 11 | NEC | 9 | 3 | 2 | 4 | 11 | 10 | 16 | |
| 12 | Heracles Almelo | 8 | 3 | 1 | 4 | 10 | 11 | 14 | |
| 13 | Go Ahead Eagles | 9 | 3 | 1 | 5 | 10 | 11 | 18 | |
| 14 | Fortuna Sittard | 8 | 2 | 2 | 4 | 8 | 8 | 16 | |
| 15 | RKC Waalwijk | 9 | 1 | 4 | 4 | 7 | 12 | 15 | |
| 16 | FC Groningen | 9 | 1 | 4 | 4 | 7 | 8 | 15 | |
| 17 | Sparta Rotterdam | 9 | 1 | 4 | 4 | 7 | 8 | 17 | |
| 18 | PEC Zwolle | 9 | 0 | 1 | 8 | 1 | 3 | 17 | |
#Schedule Eredivisie
| Date | Time | Home | Away |
| 22-10-2021 | 20:00 | Willem II | Fortuna Sittard |
| 23-10-2021 | 18:45 | FC Utrecht | SC Heerenveen |
| 23-10-2021 | 20:00 | PEC Zwolle | Heracles Almelo |
| 23-10-2021 | 21:00 | RKC Waalwijk | Sparta Rotterdam |
| 24-10-2021 | 12:15 | FC Twente | NEC |
| 24-10-2021 | 14:30 | SC Cambuur | Feyenoord |
| 24-10-2021 | 14:30 | Vitesse | Go Ahead Eagles |
| 24-10-2021 | 16:45 | Ajax | PSV |
| 24-10-2021 | 20:00 | FC Groningen | AZ |
#Results Eredivisie
| Date | Home | Away | Result |
| 17-10-2021 | AZ | FC Utrecht | 5 - 1 |
| 17-10-2021 | NEC | Vitesse | 0 - 1 |
| 17-10-2021 | Sparta Rotterdam | FC Groningen | 1 - 1 |
| 17-10-2021 | FC Twente | Willem II | 1 - 1 |
| 16-10-2021 | Feyenoord | RKC Waalwijk | 2 - 2 |
| 16-10-2021 | SC Heerenveen | Ajax | 0 - 2 |
| 16-10-2021 | Go Ahead Eagles | Heracles Almelo | 4 - 2 |
| 16-10-2021 | Fortuna Sittard | SC Cambuur | 1 - 0 |
| 16-10-2021 | PSV | PEC Zwolle | 3 - 1 |
